Abstract: We live in a matter dominated world, so where did all the antimatter go? The Hyper-Kamiokande (Hyper-K) experiment in Japan is trying to detect charge-parity violation (CPV) in neutrino oscillation, which could help explain this phenomenon. As the successor of the T2K experiment, Hyper-K produces a beam of neutrinos or antineutrinos directed towards a far detector 295 km away, which is about 8 times bigger than the current far detector, Super-Kamiokande, a water Cherenkov detector. With an expected statistical uncertainty of 3% for both neutrinos and antineutrinos, Hyper-K aims to tease out the small neutrino/antineutrino oscillation difference. In this talk, I will discuss our efforts to control systematic errors at an unprecedented level, arising from 1) neutrino beam production, 2) neutrino interaction modeling, and 3) water Cherenkov detector calibration.